convenient method for synthesis of a carbon-14 analogue of dl-phenyl alanine

Authors

gholamhossien shirvani

nuclear science research school, nuclear science and technology research institute, tehran, iran nader saemian

nuclear science research school, nuclear science and technology research institute, tehran, iran mohsen javaheri

nuclear science research school, nuclear science and technology research institute, tehran, iran

abstract

dl-phenyl alanine labeled with carbon-14 in the α-position has been synthesized from ethyl[2-14c] acetate as part of a 6-step sequence.

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part a: application of n-(p-toluenesulfonyl) imidazole (tsim) and triphenylphosphine/carbon tetrachloride in several organic transformations part b: application of 8-bromocaffeine for synthesis of some novel 8-caffeinyl derivatives

بخش اول این پایان نامه به طور عمده بر توسعه کاربردهای جدید n-(پارا-تولوئن سولفونیل) ایمیدازول (tsim) و تری فنیل فسفین/ تتراکلرید کربن در تبدیل گروههای عاملی به یکدیگر استوار است. نظر به تنوع زیاد، دردسترس بودن، سمیت کمتر و نقل و انتقال آسان تر الکل ها نسبت به آلکیل هالیدها، تبدیل مستقیم گروه هیدروکسیل به گروه های عاملی دیگر مثل آزید، نیتریل و استر یکی از مهم ترین تبدیلات در سنتزهای آلی است. با ...

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Journal title:

journal of the iranian chemical research

جلد ۴، شماره ۲، صفحات ۱۲۳-۱۲۶

Keywords

[ ' p h e n y l a l a n i n e ' , ' c a r b o n ' , 1 4 , ' d i e t h y l [ 2 ' , ' 1 4 c ] m a l o n a t e ' , ' l a b e l i n g ' ]

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